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Members in the HIV envelope glycoprotein natural degradation pathways do intensive study, a screened capable of inhibiting the degradation pathway small molecule compounds which inhibit the type I α- mannosidase activity, effectively blocking broken degrade viral envelope proteins. By further screening for type I α- mannosidase family eventually found one of his family members, 'the endoplasmic reticulum α- mannosidase I type' capable of inducing HIV envelope glycoprotein degradation, inhibiting the replication of HIV. It is understood that the endoplasmic reticulum type I α- mannosidase are glycoproteins in the endoplasmic reticulum cells carried an enzyme in the glycosylation process needed to ensure proper protein folding in the endoplasmic reticulum plays a key role. Zheng Yonghui team Researches show that the endoplasmic reticulum synthesis of HIV infected human cells in large amounts of virus envelope glycoprotein, consume large amounts of cellular resources glycosylation and folding of the induced resistance mechanism cells, resulting in the endoplasmic reticulum type I α- mannosidase activated to specifically degrade viral envelope glycoprotein, to achieve the purpose of clearing the virus. Zheng Yonghui introduction, the study found that AIDS treatment far-reaching, but also for the development of broad-spectrum anti-viral method for treating other viral infections, in particular to deal with new and unexpected, highly pathogenic viral infections, such as influenza virus, hepatitis C virus, dengue virus, the Middle East respiratory syndrome coronavirus, etc., has an important reference. Edit: SN123 The province's party members and cadres firmly support the central government decided to adhere to the rules of discipline and very enthusiastic to do in front of all the work in Hebei Hebei News Network July 25 hearing (Hebei Daily reporter) today, the provincial Standing Committee were held (enlarged) meeting and provincial meeting of leading cadres, informed the central decision on Zhou Benshun alleged serious violation of law issues organized investigation. The vast numbers of party members and cadres, said firmly support the central decision, highly consistent with the firm to Comrade Xi Jinping as general secretary of the CPC Central Committee, thoroughly implement the central major decisions and plans, and to protect Hebei reform, development and stability, energetic and promising to do Hebei work. That the province's party members and cadres, the central government decided to shun this week on suspicion of serious violation of law be set